Monitoring MMP-2 and MMP-7 levels in traumatic wounds of the ocular adnexa
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Investigation of MMP-2 and MMP-9 activities in canine sera with dilated cardiomyopathy
Dilated cardiomyopathy (DCM) is accompanied by myocytes and connective tissue changes. Matrix metalloproteinases (MMPs) play important roles in cardiac remodeling. It seems that the gelatinases (MMP-2 and MMP-9) are effective enzymes in cardiomyopathy. Dilated cardiomyopathy was confirmed in 22 dogs (patient group) including 11 female and 11 male by clinical examination, auscultation, thoracic ...
متن کاملBaclofen influences acquisition and MMP-2, MMP-9 levels in the hippocampus of rats after hypoxia.
BACKGROUND Baclofen, the agonist of GABA(B) receptors, influences hypoxia-induced deficits in learning and memory processes. METHODS We studied the effects of baclofen on acquisition in the passive avoidance test and in the Morris water maze in groups of rats without or after hypoxia as well as the influence of baclofen on MMP-2 and MMP-9 levels in the hippocampus. RESULTS Even though baclo...
متن کاملMMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE.
Development of cardiovascular disease induced by excessive Gq protein-coupled receptor agonist stimulation depends on signaling networks involving multiple matrix metalloproteinases (MMPs) and metalloproteinase disintegrins (ADAMs). Here, we hypothesized that MMP-2, being a major gelatinase in cardiac and vascular tissue, was likely to play a key role in cardiovascular homeostasis. We targeted ...
متن کاملThe relationship between MMP-2 and MMP-9 expression levels with breast cancer incidence and prognosis
The relationship between the expression levels of matrix metalloproteinase-2 (MMP-2) and MMP-9 and breast cancer prognosis was studied. Two breast cancer cell lines (MDA-MB-231 and MCF-7) and one human normal breast cell line (HS578Bst) were investigated. Fluorescence real-time reverse transcription-polymerase chain reaction (RT-PCR) and western blotting were used to detect cellular mRNA and pr...
متن کاملMMP-10, MMP-7, TIMP-1 and TIMP-2 mRNA expression in esophageal cancer.
INTRODUCTION Tissue inhibitors of metalloproteinases (TIMP) and the matrix metalloproteinases (MMP) are involved in the spread of cancer. METHODS We have evaluated the matrix metalloproteinases' (MMP-10, MMP-7) and their inhibitors' (tissue inhibitors of metalloproteinases - TIMP-1, TIMP-2) mRNA expression in 61 esophageal cancer samples from patients who had undergone surgery, by using real-...
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ژورنال
عنوان ژورنال: Oftalmologicheskii? zhurnal
سال: 2021
ISSN: ['2413-8746', '0030-0675']
DOI: https://doi.org/10.31288/oftalmolzh202151013